Orthopedics

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This quantity is a set of 22 innovative study papers from teh symposia on Nano-Biotechnology and Ceramics in Biomedical functions and Advances in Biomineralized Ceramics, Bioceramics, and Bioinspired Designs, which have been awarded on the eighth Pacific Rim convention on Ceramics and Glass expertise (PACRIM-8). The symposia used to be serious about numerous key parts, together with novel synthesis strategies, bioglasses and glass-ceramics, calcium phosphates for bone tissue functions, and oxide ceramic implant purposes. those papers minimize throughout disciplines - ceramic technology and expertise, bioengineering and nanoscience - exhibiting new, interesting box has emerged within the ceramics community.Content:

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A large difference in porosity at an intermediate range between 25 and 45% loading is noticeable between these two materials, which also exhibited a reduced level of microporosity of around 20μιη at 60% and a further reduction to ΙΟμπι at 70% solid loading. 0 i i 10 i 1 20 i I 30 1 1 40 ■ ' 50 t i 60 t m 70 i 80 Solid Loading [%] Figure 4. Measured porosity versus solid loading for CFC scaffolds at -10°C sintered at 730°C (■ Bioglass) and 1100°C ( · HAP) It was shown in previous studies23 by the author that the mean pore diameter for Bioglass increases with the increase in sintering temperature due to ease with which glass flows thus producing more interconnected 3-D porous structures.

A comparative analysis of the nature and influence of the freezing vehicle, pore structure, porosity and solid loading for the fabricated interconnected bioscaffold structures is also presented. e. rapid prototyping (RP) and conventional processing (CP), currently available for the fabrication of 3-D porous scaffold constructs using a variety of biomaterials such as alloys, ceramics and polymers. Some RP techniques can mimic the exact dimensionality of the desired tissue architecture. However, RP can often be time consuming, by and large expensive and, in some cases, are severely limited by the required spherical morphology of the feedstock together with lack of availability of some UV curable biodegradable polymer formulations, PLA and PGA, for example.

The motivation of the present work is therefore to present a brief overview of some of the current approaches available in producing porous bioscaffolds that are suitable for their use in bone tissue engineering . Furthermore, results are reported for two freeze casting techniques developed in the present investigation namely, camphene freeze casting (CFC) and water and glycerol freeze casting (WGFC) in terms of their ability to produce networked 3-D porous structures using the well known Bioglass 45S5 and hydroxyapatite (HAP).

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