By Mario Campanacci, W.F. Enneking
A scientific treatise of tumors and tumor-like lesions taking place in bone and tender tissues. The introductory bankruptcy offers the terminology, the elemental rules for category and analysis, the final rules of imaging, biopsy and histology, the staging method and assessment of the surgical margins, the final rules of curettage, neighborhood adjuvants, en bloc resection and reconstruction, chemotherapy and radiotherapy. each one pathologic entity is defined in line with its epidemiology, localization, signs, imaging, gross pathology, histopathology, histogenesis and pathogenesis, differential prognosis, direction and degree, therapy and diagnosis.
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Additional resources for Bone and Soft Tissue Tumors: Clinical Features, Imaging, Pathology and Treatment
Therefore, a completely accurate staging system does not exist. The staging system presently adopted, for benign and malignant primary tumors of bone and of soft tissues, was devised by Enneking ( 1980). e. their modality of growth, and the local reaction of the host (Enneking, 1983). Tumor growth and encapsulation Tumor growth and encapsulation depend 1) on the nature of the tumor (histogenesis and histological grade); 2) on the reaction of the host; 3) on the anatomical setting of the tumor. Tumor growth may occur by pushing (usually benign tumors) or by permeating (usually malignant tumors).
1-5). The most frequent tumor-like lesions of the soft tissues are ganglion cysts, pigmented villo-nodular synovitis, myositis ossificans, and synovial chondromatosis (fig. 1-6). 1Js2 Glomus tumor vas Solitary neurofibroma Ues Synovial hemangioma ]163 Aggressive fibromatosis u305 Neurilemoma 1J402 Lipomas 114 43 Hemangioma 0 50 100 150 200 250 300 350 400 450 Fig. 1-4. Incidence of the principal soft tissue benign tumors in our series. Superficial tumors (skin, subcutis) and outside the locomotor system are scarsely or not represented .
Positivity suggests a diagnosis of leiomyosarcoma rather than malignant peripheral nerve sheath tumor (tab. 4). Silver stain for reticulin fibers is useful in distinguishing Ewing's sarcoma from lymphoma, synovial sarcoma from fibrosarcoma, hemangioendothelioma from hemangiopericytoma. Trichrome stains for connective tissue (Mallory, Masson) are useful in cases of metastatic carcinoma and hemangioendothelioma, in order to better distinguish the cords and tubules (epithelial and endothelial, respectively) from the support connective tissue.