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Ortiz-Ortiz, M. , Moran, J. , Ruiz-Mesa, L. , Bravo-SanPedro, J. , Gonzalez-Polo, R. , and Fuentes, J. M. (2010) Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells. Neurosci. Lett. 468: 120-124. Ovbiagele, B. (2008) Potential role of curcumin in stroke prevention. Expert Rev. Neurother 8: 1175-1176. , and Eckel, J. (2008) Role of curcumin in health and disease. Arch. Physiol. Biochem. 114: 127-149. Pasic, M.

New Drugs 28: 766-782. , Hill, D. , and Zhang, R. (2007) Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by downregulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway. Cancer Res. 67: 1988-1996. Lim, G. , Frautschy, S. , and Cole, G. M. (2001) The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 21: 8370-8377. 32 Christal Sookram, Ritesh Daya, Mattea Tan et al. Lim, K. , Bar, E.

And Aggarwal, B. B. (2007) Bioavailability of curcumin: problems and promises. Mol. Pharm. 4: 807-818. , Aggarwal, B. , and Kondo, Y. (2007) Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol. Pharmacol. 72: 29-39. , Herman, T. , and Natarajan, M. (2011) Curcumin regulates low-linear energy transfer gamma-radiation-induced NFkappaB-dependent telomerase activity in human neuroblastoma cells.

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